Anaphylaxis: warning signs and an emergency action plan

Anaphylaxis is a rapidly developing, dangerous allergic reaction. Breathing problems, tongue or throat swelling, collapse or fainting require emergency help. Call your local emergency number. A rash does not have to be present.

Preparing notes for a medical appointment
Illustration: preparing questions for a clinician.

Act immediately

Use a prescribed adrenaline auto-injector according to its instructions and arrange emergency help. Say that anaphylaxis is suspected. Do not wait for an antihistamine tablet to work: it is not a substitute for adrenaline in this emergency.

NHS — anaphylaxis

Position and emergency support

Do not let the person stand or walk. Usually they should lie down; raise the shoulders carefully if breathing is difficult, and position a pregnant person on the left side. Follow the dispatcher. Start dispatcher-guided resuscitation if normal breathing stops.

NHS — food allergy

If symptoms do not improve

NHS advice recommends a second auto-injector after 5 minutes without improvement. Follow the individual action plan and device instructions. Improvement does not remove the need for emergency medical assessment; do not cancel help independently.

NHS — anaphylaxis

Prepare before another reaction

Work with an allergy specialist on triggers, prescribed devices, storage and instructions for others. With food allergy, checking ingredients and informing food-service staff are important. Do not test a suspected trigger by deliberate exposure at home.

NHS — food allergy

Your practical checklist

  • Check expiry dates on prescribed auto-injectors.
  • Practise with a trainer device.
  • Show trusted people where the action plan is and when to call emergency services.

Questions and answers

Should I wait for a rash?

No. Dangerous breathing or consciousness changes require immediate action even without visible skin changes.

Can someone stand up once they feel better?

Do not stand or walk while awaiting assessment. Stay in a safe position and follow emergency-service instructions.

Sources

  1. NHS — anaphylaxis
  2. NHS — food allergy

Sources checked on 26 September 2026.